Search results for "Biological mechanism"
showing 3 items of 3 documents
Neurobiologia e terapia dei disturbi della sfera affettiva nell'autismo: conoscenze attuali
2007
L’autismo è un disordine dello sviluppo del cervello che insorge in periodo perinatale ed è caratterizzato da disturbi del comportamento sociale, da difficoltà nelle interazioni con gli altri, da deficit del linguaggio, dalla presenza di atteggiamenti di tipo ripetitivo ed ossessivo, da alterazioni della sfera affettiva ed emozionale. L’incidenza dell’autismo ha ormai assunto le dimensioni di una vera e propria epidemia, per cui è prioritario avere a disposizione terapie realmente efficaci. Purtroppo attualmente non esiste alcun trattamento farmacologico che non sia puramente sintomatico. La carenza di farmaci efficaci è dovuto al fatto che i meccanismi neurobiologici alla base dell’autismo…
Is the Secret in the Gut? SuperJump Activity Improves Bone Remodeling and Glucose Homeostasis by GLP-1 and GIP Peptides in Eumenorrheic Women
2022
We showed that twenty weeks of SuperJump activity, an innovative workout training performed on an elastic minitrampoline, reduced bone resorption and increased bone formation in eumenorrheic women acting on the key points of the regulation of bone metabolism. The present study analyzed whether the gastrointestinal hormones are involved in the mechanism of action and if it has an impact on glucose homeostasis. The control group was composed of twelve women, similar to the exercise group that performed SuperJump activity for twenty weeks. The analysis was performed on blood samples and investigated GLP-1, GIP, GLP-2, PYY, ghrelin, glucose, insulin, insulin resistance, β-cell function, and ins…
Design of a randomized controlled trial of physical training and cancer ( Phys-Can) the impact of exercise intensity on cancer related fatigue, quali…
2017
Background: Cancer-related fatigue is a common problem in persons with cancer, influencing health-related quality of life and causing a considerable challenge to society. Current evidence supports the beneficial effects of physical exercise in reducing fatigue, but the results across studies are not consistent, especially in terms of exercise intensity. It is also unclear whether use of behaviour change techniques can further increase exercise adherence and maintain physical activity behaviour. This study will investigate whether exercise intensity affects fatigue and health related quality of life in persons undergoing adjuvant cancer treatment. In addition, to examine effects of exercise …